Cenforce 120, containing sildenafil citrate, should be avoided entirely by certain men due to potential health risks. Men with severe heart conditions, such as unstable angina, recent heart attack, or severe heart failure, should not take Cenforce, as the medication can dangerously lower blood pressure. Those using nitrate-based medications for chest pain (e.g., nitroglycerin) must avoid it due to life-threatening interactions. Men with significant liver or kidney impairment should also steer clear, as the drug may not be metabolized properly. Additionally, individuals with a history of non-arteritic anterior ischemic optic neuropathy (NAION) or severe vision disorders are advised to avoid Cenforce. Always consult a doctor first.