Silditop 100 mg, which contains sildenafil citrate as its active ingredient, typically begins to take effect within 30 to 60 minutes after oral ingestion. However, the onset time can vary depending on individual factors such as age, metabolism, overall health, and whether the drug was taken on an empty stomach. For most users, taking the tablet on an empty stomach speeds up absorption, allowing for quicker onset. Conversely, a high-fat meal may delay its effects. It is recommended to take the medication about one hour before anticipated sexual activity. Silditop 100 works only in the presence of sexual stimulation and is not an aphrodisiac.